Lianyungang Jinkang Pharmaceutical Technology Co., Ltd.

Jinkang Pharmaceutical Technology

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It's urgent for us to use active folate ( Magnafolate®) to alternative Folic Acid.

release time:2021-09-16

Folic acid is very widely used as a dietary supplement and is present in all multi-vitamin preparations. More than 80 countries have introduced legislation to fortify foods with folic acid as a public health measure to lower the incidence of neural tube defects. Low folate status is a risk factor for cognitive decline and folic acid supplements have been used to lower plasma homocysteine (tHcy) in order to prevent stroke and dementia.

However, around 30% many people have MTHFR gene mutation and need to take a few steps to convert folic acid into 5-MTHF, what our body truly need. 
Besides,  Folic acid has been reported in numerous allergies, such as rashes, itching, swelling, dizziness, dyspnea, anorexia, nausea, bloating.
Therefore, it's urgent for us to use active folate ( Magnafolate®) to alternative Folic Acid.
Magnafolate® is a patent protected C crystal form L-5-Methyltetrahydrofolate Calcium salt (Patent NO.US9150982 B2).
With the unique C crystal form, it enjoys good stability and purity. It can be stable for 3 years under room temperature. It's very important, because good stability will bring you a easier storage conditon and longer shelf life for the finished formulation. Magnafolate is the purest L-methylfolate on the planet, the purity can reach to 99%. 
It also has the highest free folate content which is higher than 85% on dry basis. 
Certification: NDI 920, Gras Self-affirmed, Halal, Kosher, ISO22000
For this  ingredient, we've finished the pre-clinical study of bioavalibility and toxicity, 3 years stability at II zone and 2 years stability at IVB zone, stability in finished formulation of tablet and capsules, dissolution Rate,etc 
Applications of Magnafolate®:
  •  Preconception care and pregnancy
  •  Heart health
  •  Depression
  •  Sleep
  •  Cognitive Improvement, Dementia & Alzheimer
  •  Replacement of Folic acid.