Calcium L-5-methyltetrahydrofolate has the unique advantage of correcting impaired folate metabolism

As the conversion of synthetic folate is affected by the enzyme folate metabolism, supplementation with inactive synthetic folate cannot meet the need for biologically active active folate in the MTHFR genetic polymorphism population. In contrast, calcium L-5-methyltetrahydrofolate, which is not affected by this metabolic enzyme, does not have the MTHFR population coverage defect and shows a more unique advantage in correcting impaired folate metabolism.

From the perspective of raw material production, due to the high threshold of core technology, since the launch of the knotted type L-5-methyltetrahydrofolate calcium in 2000, the product has been exclusively supplied by Merck in Germany and only to the European and American markets, making a significant contribution to the decline in birth defects in Europe and the US.
It was not until 2012 that the domestic Chinese company Jin Kang HeXin broke through its patented technology for the first time and established a production line for the leaf source acid brand L-5-methyltetrahydrofolate calcium C crystal type (naturalised folic acid) with independent intellectual property rights, making high quality active folic acid supplementation possible. naturalised folic acid has now been approved as a new food additive by the National Health Planning Commission. calcium L-5-methyltetrahydrofolate not only has very high stability, but also has the characteristic of instantaneous dissolution equilibrium in the medium, which improves bioavailability. More importantly, as a key patent, calcium L-5-methyltetrahydrofolate screens and removes all harmful impurities, making the product more stable and pure.
The product is more stable, purer and more bioavailable, achieving the goal of ultimate safety and efficacy, which is of great importance for key populations (MTHFR metabolic enzyme disorders), especially for pregnant women and infants who are particularly sensitive to the risk of toxicity.
Thus, naturalised folic acid will have a good preventive health and therapeutic effect on a wide range of diseases (such as birth defects, hyperhomocysteinemia and its causes of hypertension and stroke) due to the MTHFR gene mutations mentioned above.

Magnafolate is the unique patent protected C crystalline L-5-Methyltetrahydrofolate Calcium salt (L-5-MTHF Ca) which can get the purest and most stable bio-active folate.
Magnafolate can be absorbed directly, no metabolism, suitable for all kinds of people including MTHFR gene mutation.