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Calcium folinate Ingredient

Product Type  Active Pharmaceutical Ingredient
Cas No  1492-18-8
Molecular weight  511.501
Use  1. Mainly used as an antidote to folic acid antagonists (e.g. methotrexate, acetaminophen or methotrexate). 2. Used to prevent severe toxic effects caused by methotrexate overdose or after high-dose therapy. 3. Megaloblastic anemia caused by folic acid deficiency. 4. Used in combination with fluorouracil for the treatment of advanced colon and rectal cancer.
Structural formula

Calcium folinate

CAS: 1492-18-8
Molecular Formula: C20H21CaN7O7
Molecular weight: 601.58
Synonyms: Calcium folinate, Calcium methylfolate, Calcium methylfolate, Calcium aldehyde hydrofolate, Calcium formyltetrahydrofolate
Quality Standard:
Appearance Slightly yellow to yellow crystal or amorphous powder
Identification Infrared verification
Moisture Not more than 17.0%
Solubility Soluble in water, almost insoluble in ethanol
Solution color Not more than Y7
PH value 6.5-6.8
Heavy metal Not more than 0.005%
Content 95%-105